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Why use gene sequencing?

Gene sequencing is one of the methods of gene detection. It is also known as gene sequencing. It is internationally recognized as a genetic testing standard. High throughput sequencing technology is a revolutionary change in traditional sequencing, and sequencing hundreds of thousands to millions of DNA molecules at a time, known as the next generation sequencing technology (next generation). Sequencing), which shows its epochal changes. At the same time, high throughput sequencing makes it possible to analyze the transcriptome and genome of a species thoroughly, so it is also called deep sequencing. Gene sequencing related products and technologies have gradually evolved from laboratory research to clinical application. It can be said that gene sequencing technology will be the next technology to change the world.

Why do we choose strong ice technology?

  • Strong ice technology has established the leading high-throughput gene sequencing platform in China, including advanced equipment such as NovaSeq, HiSeq4000 and QuantStudio 6.
  • Strong ice technology has established a high-quality comprehensive team from top and top schools at home and abroad, with strong technical strength.
  • The high performance computing platform of strong ice technology can effectively support the demand for big data analysis in the fields of life science research and medical health.
  • Strong ice technology has a professional biological background and eight years of 菜鸟竞技平台 service experience, deep accumulation.

Gene sequencing products

Recommended sequencing platform

  • PacBio Sequel The new upgrade of the three generation sequencer PacBio Sequel, the core technology is Single molecule Real-Time (SMRT) sequencing, to achieve a single DNA molecule sequencing, and real-time monitoring of the sequencing results.
  • NovaSeq With talent, it is almost instantaneous. Learn more.
  • Ion Torrent S5 Ion Torrent S5 system, based on mature and reliable Ion Torrent technology, can complete the target sequencing process from DNA to data in 24 hours, allowing researchers to target a small number of gene sequencing or bacterial genome sequencing on Monday.

Strong ice cell sorting platform

BD FACSMelody flow cytometry

The BD FACSMelody cell sorting instrument combines the patent technology of BD high-end separator and intelligent automation software to push the simple and easy sorting instrument to a new height. Convenient operation can save the time of debugging and provide quality repeatable test results. BD FACSMelody cell sorting instrument allows more researchers to use complex flow cytometry and sorting technology to obtain more desirable cells and improve laboratory efficiency.

Strong ice single cell sorting platform

BD Rhapsody

BD Rhapsody Gamma The birth of the single cell analysis system is based on BD's 40 year expertise in the field of cell biology, and the technology of single cell capture using CytoSeq specific honeycomb panel technology. The technology uses 20W+ micropores (which are much larger than Input cells) to ensure single cell capture in single hole. At the same time, it avoids the problem of the probability impact impact capture efficiency in the traditional microfluidic system. The acquisition of microholes will have better capture efficiency and ensure the full use of Input cells.

10X Genomics

10X Genomics originated from Drop-Seq technology, through the microfluidics technology, forming oil droplets, and finally output and collected in EP tube. Each droplet will fall into a cell and a gel bead. Then, each gel bead will be covered with different sequences of Cell Barcode and UMI Barcode joining together, plus one end of PolyT grasper to form our captured gel beads.

Drop-Seq

Drop-seq was developed by a team led by Steven McCarroll of Harvard Medical School. Microfluidic devices are used to load microbeads and cells with bar code into tiny droplets. These droplets are generated on a small device and flow along a wide channel. Bar code is attached to some genes of each cell, so scientists can sequence all genes at once and track the source cells of each gene.

Reference

"Nature"

Liu Z, et Al.Autism -like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2. Nature. 2016; 4; 530 (7588): (behaviours); the Chou Zilong and Sun Qiang team built the world's first autism model;

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"Nucleic Acids Research"

Li, S.L. et al. exoRBase: a database of circRNA, lncRNA and lncRNA, et 2017.

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"Briefings in Bioinformatics"

Wu, W. et al. CASH: a constructing comprehensive splice site method site 2017 et; Doi:10.1093/bib/bbx034 (IF=5.134)

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"Genome Biology"

Gao Y, et al. Single Cas9 nickase induced generation of NRAMP1 of 2017 ET 1, 18 (1): (13.)

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"Nature Communications"

Xu C, et al. Long non-coding RNA gas5 control human embryonic human 2016, 4;

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